Comparative Study of Hemoglobin Level in Patients with Control Group Suffered from Chronic kidney Disease

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Abstract
Pharmacology, Toxicology and Biomedical Reports,2017,3,3,62-65.
Published:January 2018
Type:Original Article

Comparative Study of Hemoglobin Level in Patients with Control Group Suffered from Chronic kidney Disease

Muhammad Razi Ullah Khan1,2*, Sajid Bashir1, Syed Muhammad Aun2

1Faculty of Pharmacy, University of Sargodha, Sargodha, PAKISTAN.

2Department of Pharmaceutical Sciences, The Superior College Lahore, PAKISTAN.

Abstract:

Introduction: Hemoglobin is associated with quality of life and outcome in patients with chronic diseases including chronic kidney diseases (CKD) and end stage renal disease (ESRD), keeping hemoglobin optimal will decrease risk of complications in these patients. Objective: To monitor Hemoglobin levels monthly in sixty patients of Hemodialysis and of peritoneal dialysis and to compare quality of life between two groups of patients. Methods: This study was conducted in patients who were having chronic kidney disease on dialysis but doing follow up. Half of patients were on Hemodialysis (HD) and remaining half were receiving Peritoneal Dialysis (PD). All patients’ blood samples were done monthly for Hemoglobin level. At the same time their quality of life was assessed by three factors including their physical activity, functional activity and symptoms of the renal failure. Hemoglobin and activity standards were checked monthly. Patients hemoglobin level was compared, frequencies were calculated. Regression analysis was used for the correlation. Results: Sixty (60) patients were studied including 98(78%) and female 27(23%). Mean Age in years was 41 to 68. Out of them 43(34%) of CKD, 41(32%) on HD and other 41(32%) were on PD. Monthly mean hemoglobin levels were calculated. Relationship value of low hemoglobin with quality of life was determined. Result of effect of low hemoglobin on functional activity was significant P Value 0.000142. Conclusion: Low hemoglobin effect the functional activity while other parameters physical health and symptoms were not being affected.