@article {139, title = {Analysis of Antimicrobial Medication Consumption in Intensive Care Unit, North West (Tabuk) Region Hospitals, Saudi Arabia}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {5}, year = {2019}, month = {August 2019}, pages = {119-123}, type = {Research Article}, chapter = {119}, abstract = {

Objectives: This article describes antimicrobial medication use among different age groups and the cost associated with it in intensive care units at North West (Tabuk) hospitals, Saudi Arabia. The aim of this study to explore the antimicrobial medication use in intensive care units at North West Region Hospitals, Ministry of Health, Saudi Arabia. Methods: It is a 12-month antimicrobial drug use by intensive care units at North West region hospitals which included critical care for adults, pediatrics and neonates. The medications selected by Central Antibiotics committee at MOH as part of the National Antimicrobial Stewardship program. The consumption was driven from pharmacy database and calculated based on off standard unit of antimicrobials per hospital. The antimicrobials consisted of antibacterial drugs, antifungal and antiviral medications. The cost of antimicrobial consumption was calculated by using the Ministry of Health National Cost database. All cost used were as US currency. Results: The total number of antimicrobial standard units were (14,305) and average (2,861) per hospital. The highest drug consumption was Ceftriaxone 1 gm injection (2724) followed by Imipenem 500 mg injection (1251) and Vancomycin 500 injection (1165). The total cost of Antimicrobial consumption was (53,884.95 USD) and (10,777 USD) per each hospital. The highest cost medication consumption from Adults critical care 73.42\% (39,562.33 USD) followed by pediatrics critical care 18.15\% (9,779.93 USD) and Neonates critical care 8.43\% (4,542.68 USD). The highest medication cost was very broad-spectrum antibiotics like Meropenem, Imipenem and Ceftriaxone. It consumed more than 50\% of the cost burden. Conclusion: This study is the first in Saudi Arabia, Gulf and Middle East countries. Health system pharmacist leaders are targeting to implement the antimicrobial stewardship program and National Drug Utilization Evaluation system to control unnecessary medication expenditure and prevent misuse of medicines.

}, keywords = {Knowledge, Medications, Ministry of Health, Patient, Saudi Arabia}, doi = {10.5530/PTB.2019.5.22}, author = {Yousef Ahmed Alomi and Abeer Hussin Almasoudi and Ghormallah Abdullah Alghamdi and Samira Ali Asiri} } @article {141, title = {Analysis of Antimicrobial Medications Consumption in Inpatient Units at North West (Tabuk) Region Hospitals, Saudi Arabia}, journal = {Pharmacology, Toxicology and Biomedical Reports}, volume = {5}, year = {2019}, month = {August 2019}, pages = {130-134}, type = {Research Article}, chapter = {130}, abstract = {

Background: This article aims to explore antimicrobial medication consumption and related cost among different age groups in inpatient units at North West Region Hospitals, Ministry of Health, and Saudi Arabia. Objectives: To explore the selected antimicrobial medication consumption in inpatient units at North West Region Hospitals, Ministry of Health, Saudi Arabia. To increase the awareness of antimicrobial medication consumption side effect. Methods: It is a 9-month study about antimicrobial drug use by inpatients at North West region hospitals. It included inpatient department for adults, pediatrics and neonates. The medications were selected by Central Antibiotics committee at MOH as part of the National Antimicrobial Stewardship program. The consumption is driven from pharmacy database and calculated based on off-stranded unit of antimicrobial per hospital. The antimicrobials consisted of antibacterial drugs, antifungal and antiviral medications. The cost of antimicrobial consumption was calculated by using Ministry of Health National Cost database. All cost used as US currency. Results: The total number of Antimicrobial standard units was (25,845) and average (5,169) per hospital. The highest drug consumption was Ceftriaxone 1 gm injection (3,712) followed by Ceftazidime 1 gm injection (1807) and Gentamicin IV 80 mg (1,011) at adult{\textquoteright}s inpatient wards. The total cost of Antimicrobial consumption was (6,829,003.42 USD) and (1,365,800.68 USD) per hospital. The highest cost medication consumption from Adults inpatient departments was 99.62\% (6,803,229.92 USD) followed by pediatrics inpatient 0.24\% (16,087.6 USD) and Neonatal inpatient departments 0.14\% (9,685.9 USD). The highest medication cost was for very broad-spectrum antibiotics like Meropenem, Imipenem and Ceftriaxone. It consumed more than 50\% of the cost burden. Conclusion: There was very high consumption of antimicrobial drugs inpatient department with huge cost burden. Urgent application of antimicrobial stewardship program especially adults{\textquoteright} inpatients departments is a mandate and urgent.

}, keywords = {Antimicrobial, Consumption, Hospitals, Inpatient, Medications, Ministry of Health, North West (Tabuk), Saudi Arabia}, doi = {10.5530/PTB.2019.5.24}, author = {Abeer Hussin Almasoudi and Yousef Ahmed Alomi and Ghormallah Abdullah Alghamdi and Rasha Saad Alshahrani} }