Objective: To declare the national pharmacy research and development program as new initiatives in Saudi Arabia. Methods: It is a new initiative project of pharmacy research and development. The projects drove the international research and development guidelines, and pharmacy project guidelines of a new project and the global business model. The initial project is written through project management professionals and included several parts, including the initial phase, the planning phase, the execution phase, the monitoring and controlling phase. Results: The pharmacy research and development services that defined vision, mission, and goals. The services had multiple benefits, including clinical and economical, on the healthcare system, as described in the review. The continuation of the services assured by risk management elements description. Furthermore, the monitoring and controlling of the projects as illustrated. The transition to operation project though the closing project stage explored in the analysis. Conclusion: The pharmacy research and development program is a new initiative project in clinical pharmacy and pharmacy administration tools. The new project is useful to measure the clinical and economic of pharmacy practice and forecasting of new pharmacy programs, and it is highly recommended in the Kingdom of Saudi Arabia.