02626nas a2200253 4500008004100000245010400041210006900145260001800214300001000232490000600242520182300248653001602071653001902087653001902106653001602125653001702141100002602158700002002184700002602204700002702230700002202257700003202279856006102311 2015 eng d00aAphrodisiac Activity of Cocos Nucifera Attentuates Cerric Sulphate Induced Infertility in Male Rats0 aAphrodisiac Activity of Cocos Nucifera Attentuates Cerric Sulpha c5th May, 2015 a62-680 v13 a

Objective: In the present study, we examined the effect of hydroalcoholic extract of apical bud of cocos nucifera (HACN) in ceric sulphate induced infertility in male rats. Methods: Rats weighing 180 to 200 gm were randomized into 4 groups of 6 animals each that included saline treated rats (normal) were orally administered once daily with 0.5ml of distilled water, Ceric sulphate treated (1 mm/100 gm., s.c.) and HACN treated (200 and 400 mg/kg., p.o.). Ceric sulphate was given to the rats for 7 days for all the groups except saline treated rats then followed by administration of the HACN extract for 21 days. Parameters Evaluated: Sexual behavioural parameters including mount and intromission frequency (MF and IF) and mount, intromission and ejaculation latency (ML, IL, EL) as well as post ejaculatory interval (PEI) and body weight (BW) were recorded in male rats one hour after injection of extract by mating with a receptive female (1:1). Biochemical evaluation such as serum and cauda epididymidal testosterone and dihydrotestosterone (DHT) and histopathological analysis of testis were also assessed. Results: Ceric sulphate treated rats significantly decreased sexual behaviour and also reduced the serum and cauda epidymidal tissue testosterone and DHT when compared to control rats. All these changes were significantly attenuated by ceric sulphate rats (with HACN extract). Ceric sulphate was found to be inducing sterility in male rats which has been confirmed after analyzing all the parameters of the study. Conclusion: From the results it may be concluded that hydroalcoholic extract of cocos nucifera may be used as a good aphrodisiac activity which can promote the fertility rate.

10aAphrodisiac10aceric sulphate10acocos nucifera10ainfertility10aTestosterone1 aPrakash, Ramakrishnan1 aDheeraj, Rajulu1 aMuralidharan, Palayan1 aKarthickeyan, Krishnan1 aVijayakumar, Raji1 aPrabu, Thiraviam, Purushoth uhttps://www.ptbreports.org/article/2015/1/2/105530ptb125